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B2 · OrganisationAQA GCSE Biology · 8461 (Triple)

Stem Cells

Embryonic and adult stem cells, therapeutic cloning, ethical considerations. Paper 1. Often examined with differentiation.

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CognitoStem cells — types and uses
Key facts & methods

What are stem cells? — fill in the table

TermDetail
Stem cells
Embryonic stem cells
Adult stem cells
Meristems in plants

Medical uses of stem cells — fill in the table

AspectDetail
Bone marrow transplants
Therapeutic cloning
Advantage of therapeutic cloning
Potential future uses
Risk

Ethical considerations — fill in the table

AspectDetail
Embryonic stem cells
Argument against
Argument for
Compromise
Adult stem cells

Plant meristems (contrast) — fill in the table

AspectDetail
Location
Meristem cells
Agricultural advantage
Ethics
Exam questions — 5 questions · 11 marks · AQA 8461 style
⚡ Show all reasoning — the AI marks against the AQA mark scheme. Partial credit for correct biology even if wording differs.
1 markEmbryonic vs adultAQA 8461 style

What is the key difference between embryonic and adult stem cells?

A Adult stem cells can differentiate into more cell types than embryonic stem cells
B Embryonic stem cells can differentiate into any cell type; adult stem cells can only differentiate into related cell types
C Only embryonic stem cells are found in humans
D Adult stem cells divide faster than embryonic stem cells
4 marksTherapeutic cloningAQA 8461 style

Describe how therapeutic cloning could be used to treat a patient with a damaged liver, and explain one advantage of this approach over using donor tissue. (4 marks)

Hint: Step-by-step: source of nucleus → into egg → embryo forms → stem cells extracted → differentiate → transplant. Advantage = no rejection.
+40 XP
1 markEthical issueAQA 8461 style

What is the main ethical concern about using embryonic stem cells?

A They may not differentiate into the correct cell type
B The embryo is destroyed to obtain the stem cells, raising questions about its moral status as a potential human life
C Embryonic stem cells always cause cancer
D Adult stem cells are more effective so embryonic stem cells should not be used
3 marksBone marrow transplantAQA 8461 style

Explain how a bone marrow transplant can treat a patient with leukaemia. (3 marks)

Hint: Explain what leukaemia does, what the transplant provides, and the outcome.
+30 XP
1 markPlant stem cellsAQA 8461 style

Where in plants are the equivalent of stem cells found?

A In the leaves
B In the phloem
C In meristems at the tips of roots and shoots
D In the xylem
Quick recall flashcards

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