Watch first
▶
MyGCSEScience · AQA Biology
Drug Development & Monoclonal Antibodies — watch on MyGCSEScience
↗
FreeScienceLessons · AQA BiologyTesting Medicines
Key facts
Drug development and testing — fill in the table
| Term | Definition |
|---|
| Testing requirements | |
| Preclinical testing | |
| Clinical trials | |
| Double-blind trial | |
| Placebo | |
| Thalidomide | |
Monoclonal antibodies — production — fill in the table
| Term | Detail |
|---|
| Hybridoma cell | |
| Production | |
| Specificity | |
| Uses | |
Exam questions — 3 questions · 11 marks
⚡ Extended questions included. Read the hint. Write in full sentences. AI marks against the AQA mark scheme.
1 markDouble-blind trialAQA 8461 P1 style
Why is a double-blind trial used when testing a new drug?
A So the drug company does not know the results until the trial is finished
B To ensure neither the patient nor the doctor knows who is receiving the drug or placebo, eliminating bias from both sides
C So the drug can be tested on twice as many patients
D To test two different drugs against each other simultaneously
4 marksMonoclonal antibody productionAQA 8461 P1 Higher style
Describe how monoclonal antibodies are produced and explain why they are useful for treating cancer. (4 marks)
Hint: Production: antigen → lymphocytes → hybridoma (lymphocyte + tumour cell) → many identical antibodies. Cancer treatment: antibody attached to drug/radioactive substance → targets specific cancer cell antigens.
+40 XP
1 markThalidomide lessonAQA 8461 style
What was the main lesson learned from the thalidomide case for drug development?
A All drugs must be tested on pregnant women before approval
B Drug testing must be more rigorous and include testing for effects on pregnancy before a drug is approved
C Sleeping pills should never be prescribed
D Animal testing is not reliable and should be abandoned
Quick recall flashcards
Module complete! 🎉
Score loading...