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B6.1 · 4.6.1.1–3Paper 2🔶 Year 10 — mostly covered

DNA & the Genome

DNA structure, the genome, genes, protein synthesis. The basis of all genetics topics.

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Key facts

DNA structure — fill in the table

TermDefinition
DNA
Nucleotide
Complementary base pairs
Hydrogen bonds
Location

Genes and the genome — fill in the table

TermDefinition
Gene
Genome
Human Genome Project
Importance
Protein synthesis
Mutation
Exam questions — 3 questions · 9 marks
⚡ Extended questions included. Read the hint. Write in full sentences. AI marks against the AQA mark scheme.
1 markComplementary base pairingAQA 8461 style

A section of DNA has the sequence ATCGGA. What is the complementary base sequence on the other strand?

A ATCGGA
B TAGCCT
C UAGCCU
D TACGGT
4 marksProtein synthesis chainAQA 8461 P2 style

Describe the process by which DNA is used to synthesise a protein. (4 marks)

Hint: Two stages: transcription (DNA → mRNA in nucleus) → translation (mRNA → protein at ribosome). Mention codons and amino acids.
+40 XP
1 markGenome significanceAQA 8461 style

Why is knowledge of the human genome important for medicine?

A It allows scientists to create new genetic mutations deliberately
B It allows identification of genes associated with inherited diseases, enabling earlier diagnosis and development of targeted treatments
C It means all genetic diseases can now be cured by gene therapy
D It replaces the need for clinical trials
Quick recall flashcards

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